Integrating pathomechanical knowledge into clinical practice: arthroplasty applications

Using standardised kinematic inputs and implant alignments can limit the scope of experimental wear testing for total joint replacement. Introducing patient and population inputs, from biomechanical, clinical and retrieval studies, can enhance the predictive power of pre-clinical testing for evaluating implant performance. This abstract provides an overview of the research ongoing at the University of Leeds to optimise pre-clinical testing though the integration of pathomechanical modelling.