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Aims of this study is to classify degenerative osteoarthritis patients by logistic regression and neural network techniques using only 3-axis (medial-lateral, anterior-posterior, vertical) GRF (ground reaction force) and to develop an algorithm for predicting degenerative osteoarthritis. This test w...
Tissue stiffness is an important measurement but is difficult to measure accurately. A multiple linear regression model was developed to predict exponential growth and scale parameters. Test location, location circumference, and BMI were all significant factors in predicting local tissue stiffness.
When walking function is impaired post-stroke, the number of paretic leg muscle synergies is often reduced. However, it is unknown whether this reduction is the primary cause of impairment. In this study, we used direct collocation optimal control to generate two walking predictions using a reduced ...
Although knee injury is common among soccer players, limited research on risk of injury exists. This study examined core endurance and strength in thirty-nine professional male soccer players and recorded knee injuries experienced throughout the following season. Prone-bridge, side-bridge, trunk fle...
In this study, a ten degree-of-freedom, two-legged cyclist and bicycle model was developed and utilized for predictive dynamic simulations of standing starts. Direct collocation optimal control was used to generate the predictive simulation with the goal of maximizing distance travelled over a fixed...
We used a predictive simulation framework to explore the effect of muscle-tendon (MT) properties on gait pattern selection and cost of transport. Increased maximal muscle contraction speed and hence power induced a transition from walking to running at lower speeds. A large decrease in tendon stiffn...
It is uncertain whether low tibia osteotomy(LTO) with fibular osteotomy(FO) is more effective for the translation of concentrated pressure on medial malleolus than LTO without FO. This study quantitatively analyzes the peak pressure changes on the medial malleolus after LTO with and without FO using...
Principal component analysis (PCA) was used to compare differences in maximum reach on three different groups and 3 different loading conditions. The methodology clearly demonstrated the ability to detect differences in angle due to groups and weight moved. The aim is to develop new clinically relev...
Knee kinetics were measured in a cadaveric simulation of drop landing, in which clinically-relevant anterior cruciate ligament (ACL) injuries were obtained. A principal component analysis (PCA) was performed on the knee kinetics to identify the most relevant parameters linked to injury. The findings...
The purpose of this study was to compare the differences in produced momenta and work outputs of lower limb muscles between horizontal and vertical jumps. Horizontal and vertical squat jumps were simulated using a musculoskeletal model. The simulation results suggest that the hamstrings and rectus f...
There is a gap between the understanding of the mechanisms of sporting injury and the ability to monitor these risk parameters during a game. A wearable solution in place of captive laboratory biomechanical instrumentation would be a breakthrough for ecological validity and facilitate on-field monit...
The gross metabolic cost of walking was predicted based on dynamic simulations generated using a 3-D musculoskeletal model. While predicted costs were reasonable, the magnitude was sensitive to how closely the simulations matched the experimental data, and were also likely elevated due to simplifica...
Predictive simulations have the potential to support personalized medicine, but detailed musculoskeletal models come with large computational costs that limit their use. We have developed a computationally efficient framework to predict human gaits based on optimization of a performance criterion. O...
Equine third metacarpal (MC3) bones experience a range of surface strains which are a measure of displacement induced by mechanical loading. It is, therefore, desirable to develop an efficient, yet accurate, model in which the mechanical loading of MC3 is obtained via the induced displacement and st...
Bicycle saddle height is implicated in musculoskeletal injuries. A typical goal for setting saddle height is a minimum knee flexion angle of 30-40° during bicycling; yet dynamic analyses are unattainable in most circumstances. This investigation yielded a predictive equation, from inputs such as bi...
With great interest to the sports world, impressive performances in Athletics have drawn an interest in the gathering of kinematic data on the performances of the world’s elite competitors. This study serves as the platform in presenting biomechanical performance analysis in Athletics at the colle...
Flat feet resulting from a collapsed arch are a common concern for children with cerebral palsy (CP). Surgeries aim to restore the arch and improve pain, ambulatory efficiency, and brace tolerance. To evaluate these surgical outcomes, plantar pressures (PP) from patients indicated for a lateral colu...
The relationship between running economy and technique was explored using principal component analysis (PCA). Runners with good economy exhibit less extreme pelvis movement, reduced knee flexion mid-stance and during swing but greater knee flexion pre-landing
A probabilistic evaluation of scapulohumeral muscle functional roles revealed a high degree of sensitivity in moment arms and lines of action to alterations in musculoskeletal geometry in healthy adults. Comparisons of model-predictions against published data highlight the need to validate lines of ...
Spine kinematics are often recorded in vivo by tracking motion of multi-segment regions (e.g. T12 to S1). Many models of the spine must distribute T12/S1 motion across segmental levels, commonly by assuming linear proportions. This raises concern when modelling non-sagittal plane movements as 3-D an...
The assessment of kinetics during stair gait can only be achieved using costly force plates, which makes it difficult to implement in most clinical settings. In this study, we aimed to validate a depth sensor-driven musculoskeletal model using the AnyBody modeling system to predict three-dimensional...
High stride time variability, the integrated motor output of the locomotor system, is a factor in age-related falls. The origin of this variability remains unclear, but likely originates from variability of the motor inputs and outputs from individual muscles and joints. The gait of Italian males an...
We hypothesize that the articular surfaces of the carpals are shaped to optimally distribute contact loads. To test this hypothesis, we developed a congruence-based forward model and validated it with in vivo data. A single wrist was analyzed by taking a high-resolution MRI and three CT scans during...
During the last years, in-field motion analysis has gained more and more importance. The development of inertial sensors for motion analysis enables the measurement of motion kinematics in any environment. Although being of high importance for clinical and sports related analyses, the analysis of ki...
Ankle exoskeletons (exos) can augment human locomotion, but modeling subject-specific responses to exo torques is essential to optimize their design. Existing subject-specific modeling approaches are experimentally cumbersome or contain assumptions that limit model accuracy. We investigated the pote...
Diabetic neuropathy is one of the most common complications associated with progression of diabetes. Several approaches have been used in an attempt to predict the onset of neuropathy, peak pressure notwithstanding. Yet, prediction of this complication remains elusive. We sought to broaden the appro...
Gait variables, even temporospatial parameters, have close relationships between each variable. Previous study revealed some independent components among temporospatial parameters in normal subjects. In this study, we measured temporospatial and CoP related parameters with foot pressure measurement ...
Here we present a new musculoskeletal model of the guinea fowl pelvic limb. We use the model to explore how activation and compliance interact to influence the operating lengths and force capacity of muscle.
In sim approaches that integrate in vivo, in vitro, and in silico techniques to optimize healthcare strategies can accelerate medical advances. The present study shows that frontal plane in vivo knee kinematics identify those at risk for anterior cruciate ligament (ACL) injury; and, when combined wi...
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