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In patients with Diabetes, the accurate identification of plantar regions with abnormal loading is a crucial issue in the plantar ulcer prevention program[1,2]. We designed a peculiar mask to complement the validated anatomical mask based on the Oxford Foot Model (OFM) with a more specific forefoot ...
High stride time variability, the integrated motor output of the locomotor system, is a factor in age-related falls. The origin of this variability remains unclear, but likely originates from variability of the motor inputs and outputs from individual muscles and joints. The gait of Italian males an...
During the last years, in-field motion analysis has gained more and more importance. The development of inertial sensors for motion analysis enables the measurement of motion kinematics in any environment. Although being of high importance for clinical and sports related analyses, the analysis of ki...
It is uncertain whether low tibia osteotomy(LTO) with fibular osteotomy(FO) is more effective for the translation of concentrated pressure on medial malleolus than LTO without FO. This study quantitatively analyzes the peak pressure changes on the medial malleolus after LTO with and without FO using...
A probabilistic evaluation of scapulohumeral muscle functional roles revealed a high degree of sensitivity in moment arms and lines of action to alterations in musculoskeletal geometry in healthy adults. Comparisons of model-predictions against published data highlight the need to validate lines of ...
For individuals with cerebral palsy (CP) who experience spasticity, selective percutaneous myofascial lengthening (SPML) represents a minimally-invasive surgery targeting connective tissue surrounding muscle that may improve joint range-of-motion and walking ability. These techniques contrast with s...
Individuals after anterior cruciate ligament reconstruction (ACLR) walk using aberrant mechanics, (e.g., smaller involved knee flexion angles and moments and medial tibiofemoral joint under-loading) linked to the early development of osteoarthritis. Limited research has studied the relationship betw...
The aim of the present study was to analyze joint and segment coordination and coordination variability during gait of faller and non-faller older adults at different speeds (preferred walking speed (PWS), 120% of PWS and 80% of PWS) through vector coding technique (VC). Thirty-one young adults, 22 ...
The objective of this study was to evaluate the validity of using inertial measurement units (IMUs) to measure kinematics in the basketball free throw and to determine whether differences in technique across player calibres can be identified using these variables. Five wearable IMUs recorded 3D acce...
Disease-induced impaired hand function leads reduced quality of life and is frequently assessed by physicians in routine care of scleroderma patients. Hand movements are complex and current clinical assessments are subjective or inaccurate. A mixed cohort of scleroderma patients and healthy controls...
The aim of this study was to identify differences in plantar pressure patterns in Dutch military recruits with lower leg complaints compared to recruits without any physical complains during their basic military training. Baseline plantar pressure measurements were performed in 1142 military recruit...
When walking function is impaired post-stroke, the number of paretic leg muscle synergies is often reduced. However, it is unknown whether this reduction is the primary cause of impairment. In this study, we used direct collocation optimal control to generate two walking predictions using a reduced ...
Bicycle saddle height is implicated in musculoskeletal injuries. A typical goal for setting saddle height is a minimum knee flexion angle of 30-40° during bicycling; yet dynamic analyses are unattainable in most circumstances. This investigation yielded a predictive equation, from inputs such as bi...
Diabetic neuropathy is one of the most common complications associated with progression of diabetes. Several approaches have been used in an attempt to predict the onset of neuropathy, peak pressure notwithstanding. Yet, prediction of this complication remains elusive. We sought to broaden the appro...
The purpose of this study was to compare the differences in produced momenta and work outputs of lower limb muscles between horizontal and vertical jumps. Horizontal and vertical squat jumps were simulated using a musculoskeletal model. The simulation results suggest that the hamstrings and rectus f...
Fragility fractures pose a massive healthcare burden worldwide. Low bone quality is a major determinant of fracture risk. Bone strength, using computed-tomography based subject-specific finite-element (CT-SSFE) analysis, estimates bone quality more accurately than dual-energy X ray absorptiometry ba...
The association between asymmetries in quadriceps strength and ground reaction forces (GRF) during gait was evaluated in 11 individuals with acute anterior cruciate ligament reconstruction (ACL-R). Results indicate quadriceps weakness is associated with reduced GRF acutely following surgery. Restora...
Fundamental mechanisms that dictate the risk of spine injury, such as basic movement patterns, are affected by cognitive interference. Spine intersegmental angular change was recorded following a mechanical perturbation applied at the hands, both with and without the presence of an additional cognit...
In the lab setting, individuals with lower limb amputation (LLAs) have slower walking speed and cadence than non-amputees. However, these measures only represent a small portion of the person’s mobility during daily life. We collected walking data during the daily lives of LLAs and able-bodied con...
Reverse total shoulder arthroplasty (RSA) surgery is an effective treatment strategy for patients with varying shoulder deficiencies. The purpose of this study was to quantify the distribution of bone density in the scapulae of patients undergoing reverse shoulder arthroplasty (RSA) to guide optimal...
Aims of this study is to classify degenerative osteoarthritis patients by logistic regression and neural network techniques using only 3-axis (medial-lateral, anterior-posterior, vertical) GRF (ground reaction force) and to develop an algorithm for predicting degenerative osteoarthritis. This test w...
Predictive simulations have the potential to support personalized medicine, but detailed musculoskeletal models come with large computational costs that limit their use. We have developed a computationally efficient framework to predict human gaits based on optimization of a performance criterion. O...
Ankle exoskeletons (exos) can augment human locomotion, but modeling subject-specific responses to exo torques is essential to optimize their design. Existing subject-specific modeling approaches are experimentally cumbersome or contain assumptions that limit model accuracy. We investigated the pote...
The relationship between running economy and technique was explored using principal component analysis (PCA). Runners with good economy exhibit less extreme pelvis movement, reduced knee flexion mid-stance and during swing but greater knee flexion pre-landing
In sim approaches that integrate in vivo, in vitro, and in silico techniques to optimize healthcare strategies can accelerate medical advances. The present study shows that frontal plane in vivo knee kinematics identify those at risk for anterior cruciate ligament (ACL) injury; and, when combined wi...
Post-traumatic osteoarthritis (OA) is especially common in the trochlear cartilage of the patellofermoral (PF) joint after anterior cruciate ligament reconstruction (ACLR). The effect of walking mechanics on OA after ACLR is established in the tibiofemoral joint, but not in the PF joint. Our purpose...
Slip-induced falls are a major public health concern as approximately 25% of older adults who fall will fracture their hip [1]. There is a paucity of research investigating the upper extremity responses to a slip. The purpose of the current study was to characterize the frontal and sagittal excursio...
Because the anterior cruciate ligament (ACL) injuries occurred during sport activities imply severe consequences for athletes and the risk of reinjury in the same and in the controlateral knee is higher when returning back on the sport field, the development of screening methods to investigate neuro...
Children with Autism Spectrum Disorder (ASD) have been shown to exhibit gait abnormalities when compared to children with typical development (TD). Despite this phenomenon, few discernible gait patterns have been revealed among children with ASD. Therefore, no generalized gait characteristics have b...
Surface electromyograms (EMG) are susceptible to motion artifacts, especially during dynamic non-isometric contractions. A novel method is presented for detecting motion artifact contamination in EMG recordings. Specifically, root mean square (RMS) amplitudes of EMG recordings with two high-pass cor...
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