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People with ankle osteoarthritis (AOA) often seek surgical treatment to ease pain and restore function, and recent research has yielded relatively equal outcomes between the two primary options: ankle fusion (FUS) and total ankle replacement (TAR). One factor missing is the effect footwear has on bi...
Compared to uninjured persons, those with lower extremity amputation rely more on visual feedback to maintain balance. The purpose of this study was to evaluate center-of-mass (COM) accelerations in persons with a lower extremity amputation after the removal of visual feedback on both stable and uns...
Knee flexion and extension muscular force plays an important role in athletic performance as well as joint stability. Generally, women exhibit weaker peak force than men even after the force is normalized to their body weight. However, it is inconclusive whether there are sex differences in force st...
Surface EMGs were recorded from two muscles of the dominant lower leg during vibratory stimulation at different frequencies, while participants kept two postures on a vibrating platform. Ten vibratory sessions, combining various frequencies and postures were administered in a randomised order. RMS v...
The present study analyses how climate change aspects affect morphological and biomechanical features of bivalve shells, specifically the Chilean oyster Argopecten purpuratus. Specimens were raised in a controlled environment and exposed to different pH and temperature conditions. Morphological and ...
The study consisted of examining coxo-femoral joint kinematics, in-silico muscle force contributions and hip contact forces during level walking and squatting in femoroacetabular impingement syndrome (FAIS). Eleven symptomatic FAIS patients, and 11 healthy participants gave written consent to partic...
Lower-limb joint impedance is governed by inter-muscular length, velocity, and force-dependent feedback. These feedback pathways regulate the stiffness and damping properties of the lower-limb by modulating muscle activation. The network of length, velocity, and force-dependent feedback pathways is ...
Patella kinematics such as lateral tilt and translation may be associated with patellofemoral pain and osteoarthritis development. Physiotherapists design programs to strengthen the VMO to decrease tracking and tilt to reduce contact pressure. Using a musculoskeletal model, we estimated in vivo join...
Fundamental mechanisms that dictate the risk of spine injury, such as basic movement patterns, are affected by cognitive interference. Spine intersegmental angular change was recorded following a mechanical perturbation applied at the hands, both with and without the presence of an additional cognit...
High variability of gait motor output, such as stride time variability, occurs with aging and is a factor associated with falls in aging males and females. The mechanism is currently unclear but may be clarified by examining motor input variability. Males and females from 20 to 82 years of age compl...
Using maximum height squat jumping as an example task, it was shown that optimization of neural inputs to a largish-scale musculoskeletal model in which the actuators are represented by Huxley-type muscles, results in macroscopic behaviour similar to that of an otherwise identical model with Hill-ty...
Musculoskeletal systems (MSS) are dynamically indeterminate. For this reason, static optimization (SO) is commonly used to estimate muscle forces and activations. However, SO minimizes antagonistic coactivation, which may not be physiologically realistic. To address this issue, we developed a novel ...
This study reports a preliminary longitudinal analysis of shoulder muscles EMG onsets in patients surgically treated for rotator-cuff tear. Fourteen patients were recruited. Anterior Deltoid, Upper and Lower Trapezius onsets were collected during humerus elevation. Three sessions were completed for ...
Abnormal mechanical loading can initiate and progress degenerative joint disease. In order to predict these processes, failure thresholds for the tissues involved, including cartilage, are needed. This study used a combined experimental and computational framework to identify microscale first princi...
Surgical resection of pelvic sarcomas requires the determination of one or more cutting planes by the surgeon. The biomechanical consequences of choosing the location and angle of the cutting plane are not well known and may require attention to patient-specific conditions. This study investigated t...
Chest and abdominal wall movements have important implications for monitoring patient routines. In this regard, the use of wearable technologies combined with data analysis can be a low cost and effective option to achieve this end. Here we set out to determine the feasibility of using accelerometry...
Commonly used musculoskeletal models rely on scaled generic bony geometries, which poorly represent an individual’s skeletal anatomy. This results in erroneous joint centre location, muscle origin and insertion points, and muscle-tendon moment arm estimates leading to inaccurate biomechanical anal...
Patients who are candidates for transtibial amputation have a limb preservation option in the Intrepid Dynamic Exoskeletal Orthosis (IDEO). Power and work produced by structures distal to the knee are compared between these patient groups in this study. IDEOs and prosthetic ankle-foot devices are fo...
We propose a damped harmonic oscillator model of the acceleration of the center of mass during a medial drop landing to measure dynamic stability in subjects with functional ankle instability. We found construct validity of the model to be good. The damping coefficient in the model significantly cor...
Incorporating variable muscle coordination strategies into concurrent simulations of full body movement and joint mechanics revealed that muscle co-contraction has significant effect on knee cartilage loading during late stance in walking.
Recent studies demonstrated that transverse loading (FG) of a muscle resulted in a considerable reduction of maximum isometric muscle force (ΔFim). Here we tested if a Hill-type muscle model assuming an identical gearing G between both ΔFim and FG as well as lifting height of the load (Δh) and lo...
Movement and muscle activity involving the lumbopelvic region differ between individuals who develop transient LBP during prolonged standing, compared to their pain-free peers. However, these findings involved low-demand tasks. Challenging task variations may elicit group differences previously unse...
Energy absorption in the lower extremity during a 90 unilateral cut was assessed in collegiate female soccer players pre and postseason using a 6 degree-of-freedom (DOF) power analysis. Intervention team completed the [FIFA] 11+ during the season, control team players did not. Players in both gro...
Muscles have transient and history-dependent properties that may be important in dynamic and unpredictable interactions with the environment, such as running on uneven terrain. Hill-type muscle models do not model a variety of phenomena emergent from acto-myosin interactions, such as short-range sti...
We investigated whether surface-detected motor unit action potential (MUAP) shapes can be used to identify alterations in muscle control that occur in neuropathy and that are typically assessed using invasive needle electromyography (EMG). We found that a novel, non-invasive MUAP extraction techniqu...
Computational mechanobiological models can help to understand mechanisms leading to the progression of osteoarthritis following a joint injury. Here, we present recent advancements of in vitro and in vivo computational mechanobiological modeling of cartilage for this purpose.
Plantar fascia is related to the metatarsophalangeal joint (MTPJ) by the windlass mechanism, but the correlation between joint stiffness and diagnosis of plantar fasciitis has not been researched. In this study, passive MTPJ dorsiflexion stiffness was measured in healthy subjects and patients with p...
The results of this study suggest that ACL stiffness predicted from a combination of 3D ACL graft volume and signal intensity explains up to 80% of the variation in anterior tibial position at the time of contact during a one-leg hop-for-distance test in a cohort of ACL-reconstructed patients. This ...
This study investigated the influence of sex on tibiofemoral cartilage response to running. Healthy adults completed MR imaging of their right knee immediately before and after 15-minutes of treadmill running at a self-selected moderate pace. Pixelwise cartilage thickness maps were created from the ...
There is little known about the mechanical effects of blood flow on finger flexor tendon (FDS) and subsynovial connective tissue (SSCT) motion. Ultrasonography recorded tissue motion during middle finger flexion-extension cycles with subdiastolic venous occlusion at two speeds. Occlusion altered FDS...