Abstract Summary
Incorporating realistic skeletal kinematics and tissue property data into musculoskeletal models can improve the accuracy of mechanical load estimates. However, inclusion of subject-specific skeletal kinematics in vivo in the models may heighten the demand on the quality of tissue property input data. The current work evaluated how the inclusion of more realistic parameters within a lumbar spine model can affect calculated L4L5 net joint moments and joint reaction forces (JRFs) during a dynamic lifting motion. Results showed substantial effects of lumbar kinematics and disc stiffness on model-estimated L4L5 loads and a strong interaction.