Analysis of factors of patellofemoral instability using personalized musculoskeletal modeling

Trochlear dysplasia (TD) and medial patellofemoral ligament (MPFL) rupture are major factors in patellofemoral instability. We studied the effect of TD and MPFL rupture on PF contact pressure and kinematics in a cadaver-specific musculoskeletal knee model during a simulated non-weight-bearing knee extension motion. Peak contact pressure, but not peal lateral patellar translation, was higher in TD models compared to the normal case. Rupture of MPFL increased peak lateral patellar translation substantially in TD models. Further research will study PF factors in combination and will aim at optimizing the planning of PF instability surgeries.