Abstract Summary
We developed and validated a novel rheological model of anterior cruciate ligament (ACL) loading. The ACL force (FACL) responses to cadaveric knee loading were interpolated using novel basis functions and cross-terms to account for observed non-additivity of uni-planar loading mechanisms. Resulting functions well fit the data (R2>0.98, RMSE< 7 N) and behaved well when extrapolated (Figure 1). Final function predictions of ACL loads were accurate and physiological.