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The stretch-shortening cycle is a naturally occurring muscle-tendon function that serves to potently enhance performance, and when implemented until exhaustion results in neuromuscular fatigue that differs from that induced solely by isolated contractions. Comparable with previous reports with soleu...
Biomechanical evaluations of people with hip-related pain are often conducted in male dominated cohorts with minimal female representation. This study shows that men and women move differently with task specific differences observed at the hip and knee and consistent differences across tasks high an...
Scaling and morphing of dynamic musculoskeletal (MSK) models is an approach used to generate patient specific bone geometries for biomechanical analysis [1]. This work highlights mesh sensitivity of three methods applied to the Anybody Glasgow-Maastricht (GM) foot model [2],[3]. Each method uses a s...
We show that the metabolic cost of asymmetrical walking is greater for step time asymmetry than step length asymmetry and that the costs are not additive; rather, the metabolic cost of walking with concurrent step time and step length asymmetry is best explained by the cost of step time asymmetry al...
For understanding intervertebral disc (IVD) degeneration associated back pain and for the development of suitable treatment strategies, it is important to know how mechanical influences regulate cellular responses and their impact on disc physiology and pathology. Understanding of IVD mechano-biolog...
A deep neural network is used to segment whole slide images of plantar soft tissue sections. Morphology characteristics are computed and compared in aggregate and between diabetic and non-diabetic tissue, yielding trends in the deep adipose layer septal chambers.
Military personnel demonstrated asymmetrical knee strength and loading during landing from different dynamic tasks. Though increased knee flexion significantly improved shock attenuation, only peak knee flexion on the non-dominant limb during a single leg drop landing correlated to knee extension st...
Muscles have transient and history-dependent properties that may be important in dynamic and unpredictable interactions with the environment, such as running on uneven terrain. Hill-type muscle models do not model a variety of phenomena emergent from acto-myosin interactions, such as short-range sti...
Lower-limb joint negative mechanical powers during stand-to-sit movements were computed via inverse dynamics modelling to estimate the biomechanical energy available for regeneration with lower-limb prostheses and exoskeletons. Nine subjects performed 20 standing and sitting movements. Lower-limb ki...
Carpal tunnel syndrome (CTS) is a prevalent peripheral neuropathy due to median nerve compression. Non-neutral wrist posture and repetitive finger movement are proposed workplace risk factors for CTS. This study investigated median nerve blood flow, size, and tendon mechanics with ultrasound in 35 C...
Yunshou is a primary movement form of all kinds of Tai Chi, to which the meniscal stress response characteristic is not clear. This study applied finite element (FE) analysis with kinetic data to track the meniscal stress response during the typical Yunshou. The knee could flex with max angle of 58Â...
Different adaptation rates have been reported in studies involving ankle exoskeletons designed to reduce the metabolic cost of their wearers. The purpose of this study was to characterize energetic adaptations occurring over multiple training sessions in a novel exosuit assisting the hip joint. The ...
Existing literature has established kinematic and kinetic differences between treadmill and overground running. This study sought to investigate how metatarsophalangeal joint (MTPJ) mechanics differ between the two conditions. Range of motion, peak moment, and joint stiffness of the MTPJ were signif...
Fretting corrosion has emerged as one important reason for failure of modular hip prostheses during the last decade. This increase might be associated with the reduction of the taper diameter to improve the range of motion of the hip joint, which occurred about 20 years ago. The magnitude of the mic...
Using continuous relative phase (CRP) methodology, we quantified shank-foot couplings in time periods surrounding initial ground contact in runners wearing two shoe conditions with extreme differences in midsole cushioning levels. Non-linear mixed effects modeling was used to examine for differences...
Due to the high frequency of parastomal herniation (PSH) in colostomy patients, as well as general disagreement regarding its prevention, the application of lumbosacral orthoses (hernia belts) is explored as a non-invasive PSH prevention method of late. Five hernia belt materials were tested axially...
The goal of this research is to evaluate the effects of the Mobility Enhancing Device for Sit-To-Stand (MEDSTS); a sit-to-stand assist exoskeleton that is under development as part of this research investigation. The MEDSTS mimics the human system through the use of artificial tendons, on human loco...
Wearable device adoption is on the horizon for various populations, however there has been little consideration of long-term device impacts on the musculoskeletal system. Using a computational model, we investigated the influence of both exoskeleton device parameters and anticipated user behavioral ...
The purpose of this study is to generate a realistic human knee exoskeleton model based on a physical system, create a human-machine system (HMS) in a musculoskeletal modelling software, and simulate assistive strategies and human-machine interaction based on joint kinematics. A knee exoskeleton was...
We explored median nerve (MN) deformation and displacement during forceful gripping to better understand injury mechanisms underlying work-related carpal tunnel syndrome. 12 participants performed a chuck grip in 3 wrist positions (15° radial deviation, 0° neutral, 30° ulnar deviation) and 2 forc...
Jean Landa Pytel was one of the founders of the American Society of Biomechanics (ASB), one of the first women in the biomechanics PhD program at the Pennsylvania State University and a mentor to many women in ASB. With her passing last year, it is timely to highlight the importance of mentoring (pe...
The metabolic cost of walking is amenable to empirical curve fits, such as the increasing speed-related cost. A typical fit is derived from walking with preferred step parameters (self-selected step length and step frequency), but cannot generalize to other step parameter combinations. Mechanistic m...
This study seeks to validate a method for measuring three-dimensional knee rotations with inertial measurement units (IMUs) on human subjects and with measurements from optical motion capture (MOCAP). Unlike a prior validation conducted with an instrumented mechanical linkage, experiments on human s...
Abnormal mechanical loading can initiate and progress degenerative joint disease. In order to predict these processes, failure thresholds for the tissues involved, including cartilage, are needed. This study used a combined experimental and computational framework to identify microscale first princi...
Soft-tissue vibrations generate discomfort and thus require a greater muscle contribution to preserve an efficient motion. Besides, this may lead to an earlier onset of muscle fatigue. As a matter of fact, reducing tissue vibrations is of great interest from a comfort and performance standpoint. Thi...
This study investigated the minimum sensor configuration (individual or pair) to achieve the simplest cost-effective sensor fusion configuration for robust gait event detection. Five sensors were attached to a powered ankle-foot orthosis: foot IMU, shank IMU, ankle potentiometer, heel contact sensor...
The mechanisms governing the attraction of biological molecules remain an open question in biophysics and chemistry, particularly in the case of actin and myosin. These molecules have characteristic lengths on the order of 10 nm, suggesting that they are subject to thermal agitation, Hamaker, and el...
Muscle excitations are distributed heterogeneously within the muscle, resulting in local differences in the amplitude of surface electromyograms. The functional significance of regionalized muscle excitation may be studied with high-density recordings, but these data are high-dimensional, making the...
Climbing is a sport requiring strength, flexibility, and coordination. Because children with cerebral palsy have deficits in each of those areas, climbing was proposed and evaluated as a recreational therapy. Participants completed a uniform set of lateral and vertical steps (8 to 16 in). Limb force...
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