Synthesis and characterization of a polymer scaffolding by electrospinning for the formation of ligament

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Abstract Summary
Ligament rupture is among the most common musculoskeletal problems. Nevertheless, an ideal graft transplant helps to bring the patient back to normality. Nowadays, two types of graph transplants are used, however, they both present disadvantages: autograft, tends to lose their mechanical resistance when being cultivated, while allograft has a high probability of being rejected by the patient. The present study focuses on the synthesis and characterization of polycaprolactone/chitosan nanofibers by electrospinning, to have a polymeric ligament with mechanical properties like a normal ligament. In this work, we obtained a polymer scaffolding for the formation of ligament with a maximum tension of resistance of 11.46 MPa with a solution of polycaprolactone and chitosan in a ratio of 80:20 wt / wt respectively, which indicates that we are in 12% to reach the resistance of the tension of an anterior cruciate ligament.
Submission ID :
UCB2213
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