Electromechanical effects of heterogeneous human ipsc-derived cardiomyocyte couplings

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Abstract Summary
Human induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) tissue consists of heterogeneous CMs coupled by gap junctions. Electromechanical effects of these couplings are estimated using a computer model. Simulations suggest that the electromechanical variability in the tissue is decreased by gap junctional couplings depending on the conductance and the number of different CMs.
Submission ID :
UCB1945
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Poster-Aug3

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