Abstract Summary
Effect of surface profile of a Co-28Cr-6Mo alloy (ASTM F-75) disc on wear behavior of an ultra-high-molecular-weight polyethylene (GUR1050) pin was investigated by using a pin-on-disc wear testing machine with multi-directional pathways. The surface of a Co-28Cr-6Mo alloy disc had a waviness curve from the millimetre to micrometre scale and a surface roughness of the nanometre scale, which was processed by micro slurry jet (MSJ). It was elucidated that the Co-Cr-Mo alloy surface processed by MSJ reduced the specific wear rate of polyethylene. The wear particles isolated from the lubricating liquid were added to a culture medium, and human monocyte-derived macrophages (HMDM) were incubated by using an upright/inverted method. The production of TNF-α and IL-6 seemed to have a correlation with the amount of wear particles added.