Abstract Summary
The aim of this study was to establish the relationship between asymmetries in muscle strength, activation, and joint kinetics during running. Between-limb differences in peak sagittal plane ankle and knee joint moments during running, isometric plantarflexor and knee extensor strength at three knee angles, and muscle activation of 8 lower limb muscles were analysed using discrete point and time-series analysis. Large observed between-limb differences in joint moments and isometric strength were not correlated. Only tibialis anterior activation was different between limbs. Preferred limb plantarflexors were stronger at 5 and 25⁰ of knee flexion but preference was not evident at the knee joint or during running. Asymmetry during one test condition should not be extrapolated to indicate asymmetry in another.