Abstract Summary
The purpose of this research is to evaluate the influence of surface condition of culture substrate on cell adhesion, cell activity and cell differentiation. It is well known that photofunctionalization on surfaces promotes the osteogenesis. It is common knowledge that cells strongly adhere to UV irradiated substrate because UV surface modification improves affinity of titanium surface and cells. However, there are not many studies investigating the influence on cell dynamics and cellular activity changes by UV irradiation. In this research, a substrate treated with various UV irradiance conditions was used for evaluation. The cell activity and cell differentiation were evaluated using a fluorescence microscope and absorbance measurements. As a result of the experiment, Cell adhesion effect to substrate was improved by UV irradiation. The cell activity and cell differentiation effects were changed by dependence on the irradiation time.
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