A randomized controlled trial to compare the effect of non-operative treatment with or without platelet-rich plasma on healing and function in patients with acute achilles tendon ruptures

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Abstract Summary
The use of platelet-rich plasma (PRP) injections in the treatment of acute Achilles tendon rupture (ATR) remains controversial. This double-blinded, randomized controlled trial aimed to compare the effectiveness of PRP versus placebo injections in non-operatively treated ATR patients. Estimates of tendon healing, functional, and patient-reported outcomes were slightly more favourable in the PRP group at most time points.
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UCB890
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