A three filament muscle model based on a titin-myosin interaction

This abstract has open access
Abstract Summary
The mechanical impedance of active muscle affects the stability of musculoskeletal systems to perturbations. Following a recent experimental finding, we have developed a three filament muscle model in which myosin loads titin when shortening and clutches onto titin during lengthening. A virtual active lengthening experiment indicates that this mechanism can explain the steady increase of force during muscle stretching but that the model is missing terms related to residual force enhancement.
Submission ID :
UCB2186
Select an Abstract Type
Select a Topic

Abstracts With Same Type

Submission ID
Submission Title
Submission Topic
Submission Type
Primary Author
UCB1506
Wireless sensors and wearable devices
Oral
Rachel Horenstein Rachel Horenstein
UCB866
Modeling: General and simulation
Oral
Karim Makki* Karim Makki*
UCB1015
Biomedical engineering
Oral
Sarvenaz Chaeibakhsh* Sarvenaz Chaeibakhsh*
UCB753
Running: Biomechanics
Oral
Victoria Chester* Victoria Chester*
UCB1328
Modeling: Musculoskeletal
Oral
Alexis Brierty Alexis Brierty