Intramuscular pressure of human tibialis anterior muscle reflects aging related muscular changes

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Abstract Summary
This study aimed to test whether intramuscular pressure (IMP) represents aging related changes by stimulating the fibular nerve and measuring ankle torque, compound muscle action potential (CMAP), and IMP from TA of healthy young (20-40 years old) and older (60-80 years old) adults. It was found that CMAP, torque, and IMP increase with increasing stimulation intensity for both young and older adults (p < 0.001 for all tests). Similar to CMAP and ankle torque, the TA IMP was significantly lower for older adults (by 24%). Our findings suggest that IMP is a minimally-invasive method that detects aging related muscular changes and can provide a measure of muscle dysfunction.
Submission ID :
UCB2122
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