Load induced changes in articular cartilage biomarkers before and after high tibial osteotomy in patients with medial compartment knee osteoarthritis

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Abstract Summary
Our loading experiment in patients with medial compartment knee osteoarthritis before and after high tibial osteotomy revealed that not only COMP but also MMP-3, MMP-9, C2C, CPII, PRG-4 and IL-6 are sensitive to a walking exercise and that the pre-to postoperative change in knee adduction moment is associated with the pre- to postoperative change in load-induced increase in COMP.
Submission ID :
UCB2012
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Oral
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Neuromuscular: Muscle

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