Personalization improves the efficacy of gait modifications at reducing the knee adduction moment in individuals with medial knee osteoarthritis

Medial knee osteoarthritis (mKOA) progression is linked to a¶ high peak knee adduction moment (pKAM). Toe-in and toeout¶ gait modifications can reduce the pKAM, but prescribing a¶ uniform modification to an entire cohort has yielded mixed¶ clinical outcomes. Our study investigates the efficacy of¶ personalized foot progression angle (FPA) modifications in¶ reducing the pKAM. Eighty-eight individuals with mKOA¶ walked on a treadmill naturally, then with 5° and 10° of toe-in¶ and toe-out. With a personalized FPA modification, 72% of¶ the cohort reduced their pKAM which was more (p< 0.001)¶ than the 57% and 25% that reduced their pKAM with a¶ uniform toe-in and toe-out modification, respectively. The¶ personalized selection of gait modifications may improve their¶ efficacy in slowing the progression of mKOA.