Abstract Summary
Kinematic and electromyography data were collected from people without transtibial amputation (TTA) and with TTA for three prosthetic alignment conditions during sit-to-stand (STS). People with TTA had greater amputated side and lower intact side rectus femoris activity compared to people without TTA. Changes in amputated side muscle activity in response to alignment shifts suggest that lateral shifts reduce muscular effort associated with maintaining stability during STS.